Comment:
The liver has an important role in the metabolism of many exogenous drugs and endogenous hormones by virtue of several enzyme systems involved in biochemical transformation. LD-477 is a traditional formula for clearing away internal heat and toxin from the liver and gallbladder system, and assisting the liver's detoxification mechanisms. The ingredients, Bupleuri Radix, Forsythiae Fructus, Scutellariae Radix, Coptidis Rhizoma, Gardeniae Fructus and Trichosanthis Radix are popular herbs to detoxify endogenous toxin. Other ingredients have the function of promoting blood circulation, inducing urination and speeding up the excretion of internal toxins.

Indications:
Endogenous toxin, lymphadenitis, chronic tonsillitis, skin diseases, viral infection.

Dosage:
4-6 tablets three times per day, before meals.

Functions
Traditional:
     Clears away heat and toxin, dispels wind-heat, promotes blood circulation.
Modern:
     Assists the liver to detoxify endogenous toxin and speeds up the excretion of internal toxins.

Chinese Medical Description:
Bupleurum
     Drains heat from the Liver, soothes the Liver and reduces fever
Tang-Kuei, Peony, Cnidium, Rehmannia
     Nourishes the Blood and promotes blood circulation
Scute, Coptis, Phellodendron, Gardenia, Forsythia
     Clears away Heat and Toxins
Trichosanthes, Alisma
     Clears Heat, subdues swelling and induces diuresis
Mentha
     Dispels Wind-Heat
Arctium
     Dispels Wind-Heat; clears away Heat and toxins
Platycodon
     Facilitates Lung Qi and promotes pus discharge
Licorice
     Clears away Heat and Toxins